HEPATITIS OF MALARIAL ORIGINClinical and Pathologic Study of Fifty-Four Korean Veterans
ARTHUR E. McMAHON, Jr., M.D.;
JAMES E. KELSEY, M.D.;
DONALD E. DERAUF, M.D.
AMA Arch Intern Med. 1954;93(3):379-386.
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HEPATITIS is the most significant feature of malaria now that drgus capable of eradicating the parasite from the body have been developed. Rapid presentday therapeutic measures fail to take cognizance of the fact that the hepatitis may be more incapacitating than the acute episode of parasitemia.
Malaria has been found in 6.6% of returning Korea veterans.1 Early in our experience with these patients we were impressed with the high incidence of abnormal hepatic function. The literature was reviewed, and numerous references concerning liver disease in malaria were found.* Most of these referred to hepatic dysfunction complicating malarial fever therapy of tertiary syphilis.
Lippincott and co-workers reported transient abnormal hepatic function in 317 cases of chronic relapsing Plasmodium vivax malaria. Other authors investigating hepatic dysfunction in malaria either did not perform extensive tests of liver function or did not obtain liver biopsy specimens.
MATERIALS AND METHODS
Fifty-four Korea veterans with malaria
. . . [Full Text PDF of this Article]
Author Affiliations
DES MOINES, IOWA
From the Department of Internal Medicine, Veterans Administration Hospital.
Footnotes
Sponsored by the Veterans Administration with the approval of the Chief Medical Director. Statements and conclusions by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration.
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