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A. ROTTINO, M.D.; A. JOFFE, M.D.; G. HOFFMANN, M.D.

AMA Arch Intern Med. 1954;93(4):561-570.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

IT IS THE purpose of this paper to present an evaluation of the therapeutic efficacy of phenylbutazone* in Hodgkin's disease. The study covers a period of 18 months, during which time sufficient data were accumulated on 35 patients with Hodgkin's disease to make evident a pattern of therapeutic response and to delimit its usefulness insofar as this disease is concerned.

We shall not review the literature pertaining to the chemistry or pharmacology of phenylbutazone nor its effects on diseases other than Hodgkin's disease. This has been done adequately by others, but up to now only one reference³ has appeared in the literature as to its effect on Hodgkin's disease. This one report states briefly that after a single intramuscular injection of the drug into one patient with Hodgkin's disease there followed reduction of fever, subsidence of pain, and improvement of general condition and appetite.

MATERIAL

In Table 1 are . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Hodgkin's Disease Research Laboratory and the Department of Medicine, The St. Vincent's Hospital of the City of New York.

Footnotes
Supported by Grants from the Damon Runyon Memorial Fund and the American Cancer Society.

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