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Relationship to Secondary Amyloidosis and Report of a Case

HOBART A. REIMANN, M.D.; PHILIP F. SAHYOUN, M.D.; HRANT T. CHAGLASSIAN, M.D.

AMA Arch Intern Med. 1954;93(5):673-686.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

AMYLOIDOSIS is classified into groups, as primary, secondary, localized or tumor-forming, and the kind associated with plasmacytoma.¹ The clinical characteristics of each group usually are distinctive enough to set it apart, but other features suggest a closer relationship than is apparent. Clinical differentiation between primary and secondary amyloidosis is of more than academic interest. Recovery from the primary form has not been reported, and amyloidosis secondary to other disease is reversible and may disappear if the cause is removed before the process is too far advanced.²

Primary amyloidosis, as its name implies, is not preceded by a discernible cause. Amyloid accumulates slowly over years in and around blood vessels and in tissue of mesenchymal origin generally. The disease becomes clinically evident chiefly in middle-aged or aged persons. Similar amyloidosis occurs spontaneously in senile mice.³

The secondary form is encountered most frequently and occurs chiefly in young adults. . . . [Full Text PDF of this Article]

Author Affiliations
BEIRUT, LEBANON

From the American University Hospital.

Footnotes
References 5-8.

References 9-12.

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