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Review of the Recent Literature

HERMAN BEERMAN, M.D.; IRA L. SCHAMBERG, M.D.; LESLIE NICHOLAS, M.D.; LAWRENCE KATZENSTEIN, M.D.

AMA Arch Intern Med. 1954;93(5):742-780.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PROPHYLAXIS

THAT PROGRESS in the field of prophylaxis of syphilis is being made is indicated by two pertinent recent publications. In an editorial in the American Journal of Syphilis, Gonorrhea and Venereal Diseases²³⁰ concerning oral administration of penicillin in the prophylaxis of syphilis, the editor points out that while a single penicillin tablet ingested soon after exposure has been demonstrated to be highly effective in the prevention of gonorrhea and has been widely used in the Navy for this purpose such a method is not effective in the prophylaxis of syphilis. Weinstein and his co-workers²⁵³ have shown that 6,750,000 units of penicillin, administered by mouth, in conjunction with fever, is ineffective treatment for primary and secondary syphilis. Much less treatment is need to cure syphilis in the early incubation period. It is estimated that an amount of penicillin sufficient to provide blood penicillin levels of 0.2 per milliliter for a period . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA; WILMINGTON, DEL. With the Collaboration of Frank W. Reynolds, M.D., and T. Guthe, M.D., Geneva, Switzerland.

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