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ISIDORE SNAPPER, M.D.; LIEUTENANT COLONEL WILLIAM G. BRADLEY; VERNON E. WILSON, M.D.

AMA Arch Intern Med. 1954;93(6):807-817.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INTEREST in the problem of the deposition of calcium in abnormal locations, that is, in subcutaneous tissue and visceral organs, has been revived by the relatively recent publication of Burnett and associates of a study of six cases of metastatic calcification related to excessive ingestion of alkali and milk in patients with ulcers of the stomach.⁶

GENERAL COMMENTS ON METASTATIC CALCIFICATION

Metastatic calcification may be caused by many different conditions in addition to that listed above, and the following ailments should be mentioned: ( 1) administration of excessive amounts of vitamin D; (2) hyperparathyroidism; (3) chronic renal disease in young persons, leading to long-standing acidosis; (4) complete immobilization in patients with fractures treated with extensive plaster casts or during wide-spread paralysis in poliomyelitis; (5) chronic lower nephron nephrosis or so-called tubular acidosis.¹⁷

Metastatic calcification also occurs in rapidly spreading osteolytic malignant lesions of the skeleton. The tendency to metastatic . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO; MEDICAL CORPS, UNITED STATES AIR FORCE; CHICAGO

From the Department of Medicine, University of Illinois School of Medicine, Research and Educational Hospitals.

Footnotes
References 4 and 11.

References 1, 13, and 18.

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