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CLAUDE-STARR WRIGHT, M.D.; D. SHELTON MABRY, M.S.; RICHARD D. CARR, M.D.; ANNA MAE PERRY, B.S.

AMA Arch Intern Med. 1954;94(6):995-1036.

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WHITE BLOOD CELLS

Chemical Observations on Leucocytes.

—Rottino makes a pertinent suggestion: "A fruitful field for research would be one which still lies on the frontiers of the unknown—namely the physiology of the lymphoid system." ⁶⁹⁹ This is equally applicable to the physiology of the other white cells. Too long has our research been dominated by the empiric approach.

Microspectrophotometric estimation of the deoxyribonucleic acid (DNA) content of individual normal human lymphocytes discloses that such cells contain twice the average DNA content of normal human spermatids.⁷⁰⁰ Nucleic acid content of splenic lymphocytes has been studied in mice.⁷⁰¹ A report concerning stable sudanophilia of human neutrophile leucocytes in relation to peroxidase and oxidase concludes that the sudanophilia of leucocytes is as yet unexplained.⁷⁰² Other extensive cytochemical studies have been made by Storti and co-workers.*

Carbohydrate metabolism of leucocytes has been comprehensively reviewed.⁷⁰³ Studies . . . [Full Text PDF of this Article]

Author Affiliations
COLUMBUS, OHIO