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ROBERT F. NEJEDLY, M.D.; LYLE A. BAKER, M.D.

AMA Arch Intern Med. 1955;95(1):37-40.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE TREATMENT of histoplasmosis, particularly of the progressive disseminated type, has been for the most part unsuccessful. In vitro studies by Seabury and Artis ¹ revealed that stilbamidine is an effective histoplasmocidal agent, and Snapper has shown that 2-hydroxystilbamidine inhibits the growth of histoplasma capsulatum in vitro in concentrations of 20 to 40 per milliliter.² Because of these findings and inferred benefit from stilbamidine in disseminated cases, we felt that a clinical trial with 2-hydroxystilbamidine was indicated in a case of localized histoplasmosis of the hard palate recently admitted to the Veterans Administration Hospital, Hines, Ill.

REPORT OF A CASE

A 53-year-old white man, a cattle farmer from Nebraska, first noted a painful area involving the gingiva in the region of his left upper premolar teeth in May, 1953. A small nodule developed in this area, and approximately one month after onset of symptoms it became ulcerated. At . . . [Full Text PDF of this Article]

Author Affiliations
Hines, III

From the Veterans Administration Hospital.