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Tuberculous Pleurisy with Effusion
J. ARTHUR MYERS, M.D.
AMA Arch Intern Med. 1955;96(2):191-201.
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PATHOGENESIS
When tubercle bacilli invade the body by any portal of entry they are ingested by neutrophiles, many of which enter the blood stream and are soon focalized in various places. More focalizations occur in the lungs than in any other organ. Lemon and Montgomery 1 found that when tubercle bacilli are placed into pleural spaces of normal rabbits they are soon phagocytosed and some are deposited in lymph nodes and remote organs. Others have observed that when tubercle bacilli are introduced subcutaneously or directly into the stomach or intestines, many may soon be found in the lungs and elsewhere about the body where they have been focalized. Tubercles are formed at the points of focalization and may harbor bacilli for long periods. At any point of focalization where bacilli remain alive they may at a subsequent time be liberated and disseminated to immediate and remote areas.
Inasmuch as many
. . . [Full Text PDF of this Article]
Author Affiliations
Minneapolis
From the Student Health Service, School of Public Health, and Department of Medicine, University of Minnesota.
Footnotes
Submitted for publication May 6, 1955.
Prepared with the aid of the H. Longstreet Taylor Foundation, established by the Minnesota Tuberculosis and Health Association.
Presented in part before Postgraduate Course, Clinica Antillas, Rio Piedras, Puerto Rico, March 14, 1955, and Wisconsin Chapter, American College of Chest Physicians, Milwaukee, May 1, 1955.
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