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Thrombophlebitis Migrans and Visceral Carcinoma
ROBERT H. DURHAM, M.D.
AMA Arch Intern Med. 1955;96(3):380-386.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Many clinicians have had occasion to observe that patients who have carcinoma involving an internal organ are prone to develop thrombophlebitis in one or more superficial veins. Trousseau* first wrote about this observation 94 years ago. In brief, he stated that, if the diagnosis of a suspected carcinoma of an internal organ could not be verified, the sudden and spontaneous appearance of thrombophlebitis in a larger vein afforded necessary proof for diagnosis. Trousseau's basic observation stands, but in the light of our present knowledge certain other facts may be added to his statement. For example, the appearance of one or more lesions of thrombophlebitis may be the first tangible evidence of the presence of a visceral carcinoma. It is, therefore, the obligation of the clinician to classify as accurately and as early as possible any type of thrombotic lesion encountered.
There are two types of thrombotic lesions whicharecarcinogenetic in origin.
. . . [Full Text PDF of this Article]
Author Affiliations
Detroit
From the Division of General Medicine, Department of Medicine, Henry Ford Hospital.
Footnotes
Submitted for publication June 20, 1955.
This paper was discussed by Dr. J. Earl Estes Jr., of Rochester, Minn., and by Dr. William T. Foley, of New York.
Read before the Section on Internal Medicine at the 104th Annual Meeting of the American Medical Association, Atlantic City, June 10, 1955.
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