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LAURANCE W. KINSELL, M.D.; JOHN P. JAHN, M.D.

AMA Arch Intern Med. 1955;96(3):418-427.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

TO HAVE practiced medicine during the past quarter century has been a privilege and an exciting experience. During that period, there has been a striking change of emphasis from tissue pathology to physiology and biochemistry. In association with this, therapeutic nihilism has been replaced by a dynamic and effective pharmacology. The two fields in which the most rapid advances in Pharmacologic theory and practice have occurred are those of antibiosis and endocrinology.

Those physicians who received their training and who practiced medicine in the period preceding the antibiotic era can well recall the feeling of inadequacy inspired by an average patient with Pneumococcus pneumonia and, to a much greater degree, by the patient with bacterial meningitis or Staphylococcus septicemia.

Following upon the initial demonstration of the effectiveness of sulfanilamide, increasingly potent chemotherapeutic and antibiotic agents became available at an amazing rate. As a result, the clinician may now approach the . . . [Full Text PDF of this Article]

Author Affiliations
Oakland, Calif.

From the Institute for Metabolic Research of the Highland Alameda County Hospital; Schering Research Fellow, July 1, 1952, to June 30, 1953 (Dr. Jahn).

Footnotes
Submitted for publication May 25, 1955.

Original work reported here has been carried out in association with Drs. Walter C. Adams, Harry E. Balch, Philip N. Baxter, Lenore A. Boling, Bruce M. Fisher, Nadine Foreman, Arthur J. Hunnicutt, william E. Iaconetti, William A. Leovy, Thomas R. Meagher, H. Harvey Peterson, Albert E. Thill, Gregory Thomas, and Himeo Tsumori.

This work has been supported in part by grants from the Armour Laboratories; Merck & company, Inc.; Schering Corporation; Pfizer Laboratories, Division of Chas. Pfizer & Company, Inc., and The Upjohn Company. Acknowledgement is made for the following supplies: ACTH from the Armour Laboratories; cortisone and hydrocortisone from Merck & Company, Inc., Chas. Pfizer & Company, Inc., and The Upjohn Company, and 1-cortisone and hydrocortisone (prednisone [metacortandracin] and prednisolone [metacortandralone], respectively) from the Schering Corporation.