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  Vol. 96 No. 6, DECEMBER 1955 TABLE OF CONTENTS
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Significance of Diphtheroids in malignant Disease Studied by Germ-Free Techniques

Reevaluation in Hodgkin's Disease, Lymphoma, and Mouse Carcinoma

ROBERT KASSEL, Ph.D.; ANTONIO ROTTINO, M.D.

AMA Arch Intern Med. 1955;96(6):804-808.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A survey of an extensive literature on Hodgkin's disease shows it to contain many publications reporting implication of bacteria as the etiologic agent.* None of the work, however, has stood the test of time. Pertinent to our own study are the more recent reports concerning the isolation of acid-fast organisms25 and of a "diphtheroid" 7 from the blood of patients with Hodgkin's disease, since, for a period of time, a diphtheroid with acid-fast properties was persistently isolated by us in blood cultures not only from patients with Hodgkin's disease but from patients with leukemia and lymphosarcoma as well and from both patients and mice with cancer.

It would serve no purpose to describe in detail the numerous experiments performed during four years in an attempt to determine whether these organisms really were carried in the blood stream of sufferers from Hodgkin's disease. The description and results of two major . . . [Full Text PDF of this Article]


Author Affiliations

New York

From the Dorothy H. and Lewis Rosenstiel Foundation-St. Vincent's Hospital Hodgkin's Disease Research Project.


Footnotes

Submitted for publication July 15, 1955.



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