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A Seven-Year Experience

WILLIAM H. BEIERWALTES, M.D.; PHILIP C. JOHNSON, M.D.

AMA Arch Intern Med. 1956;97(4):393-402.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

More than 14 years have elapsed since Hertz ¹ and Hamilton ² first used radioiodine to treat thyroid disease. During this time reports ³ have been published on the treatment of more than 1700 hyperthyroid patients with radioactive iodine, I¹³⁰ and I¹³¹. Yet many questions remain unanswered. Does radioiodine, I¹³¹, cause cancer of the thyroid gland 10 to 20 years after a dose of I131 is given for the treatment hyperthyroidism?⁴ Should one aim to "cure" the hyperthyroidism with one dose, or should multiple small doses be used to avoid a high incidence of hypothyroidism? Do severely hyperthyroid persons with an unusually high I¹³¹ uptake require a smaller or larger dose of radioiodine than the average patient?⁵ Should radioiodine be used as preoperative preparation for toxic nodular goiters?* Will a substernal goiter disappear by the time I¹³¹ therapy has rid the patient of thyrotoxicosis? Is the I¹³¹ method of relieving . . . [Full Text PDF of this Article]

Author Affiliations
Ann Arbor, Mich.

From the Department of Internal Medicine, University of Michigan Medical School.

Footnotes
Received for publication Oct. 6, 1955.

The expense of this study was defrayed in part by grants from the Michigan Memorial Phoenix Project.

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