This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (138)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A New Heredofamilial Syndrome

EZRA SOHAR, M.D.

AMA Arch Intern Med. 1956;97(5):627-630.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A CLINICAL syndrome characterized by progressive deafness, ophthalmological changes, and laboratory evidence of chronic renal disease has been observed and studied in four brothers. The results of clinical and laboratory investigations conducted while these patients were hospitalized yielded an almost identical picture in all four siblings. At the time of investigation, their ages were 18 (J.), 17 (I.), 16 (N.), and 14 (M.).

In all instances, deafness was first noted at age 9 to 10 and was progressive. The youngest brother (M.) in addition had had intermittent back pain since the age of 12 (once with hematuria?) and amebic colitis at the age of 13. Physical examination in all instances revealed normal physical development, asthenic build, long extremities and fingers, and high palate. Their weights ranged from 55 kg. in the oldest to 40 kg. in the youngest. An apical systolic murmur was audible in all except N. A positive . . . [Full Text PDF of this Article]

Author Affiliations
Tel-Aviv, Israel

Footnotes
Submitted for publication Sept. 20, 1955.

Department of Medicine, Tel-Hashomer Government Hospital; Present Address: The Mount Sinai Hospital, New York.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?