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D. B. HORSLEY, M.D.; OLDRICH PREC, M.D., Ph.D.

AMA Arch Intern Med. 1956;97(6):806-813.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

RECENTLY published reports have described a predominantly right-sided valvular heart lesion associated with cancerous argentaffinoma of the bowel.* These patients had some skin disorder such as intermittent cutaneous vasomotor flushing and/or a peculiar type of mottled cyanosis. There is a tendency to consider this combination of lesions as a new clinical syndrome. Some of the skin manifestations can be explained by a hormonal secretion, 5-hydroxytryptamine, of the argentaffinoma tumor.¹⁰ The relationship between the tumor and the heart lesion is obscure. More clinical studies are needed to evaluate this rather rare combination of diseases. This paper reports an additional case which has been extensively studied and includes references not mentioned in previous reports.

REPORT OF CASE

A 54-year-old white woman was well until November, 1953, when she developed edema of the lower extremities, exertional dyspnea, and sub- sternal pressure sensations. Orthopnea was not present. Shortly afterwards she had episodes of . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

From the Cardiovascular Research Laboratory, St. Luke's Hospital, and the Department of Medicine, University of Illinois College of Medicine; Senior Resident in Medicine, St. Luke's Hospital (Dr. Horsley), and Director of the Cardiovascular Research Laboratory, St. Luke's Hospital, and Lecturer-Assistant Professor of Medicine, University of Illinois College of Medicine (Dr. Prec).

Footnotes
Submitted for publication Nov. 5, 1955.

Dr. Edwin F. Hirsch, Director of Pathology, St. Luke's Hospital, gave permission to include the autopsy findings in our case and made criticisms and suggestions in the preparation of this paper.

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