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EDWARD D. FREIS, M.D.

AMA Arch Intern Med. 1956;98(4):444-448.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The purpose of antihypertensive drug therapy is to lower the blood pressure safely and within the limits of tolerable side-effects. This attainment, however, requires a technique which is even more specialized than our present-day methods for controlling diabetes. The technique is based on the following principles.

Technique of Antihypertensive Drug Therapy

1. Individual Differences.

—Some patients will respond best to one type of antihypertensive agent, others to another. In addition, the dosage requirement may differ markedly from one patient to another. The duration of the blood pressure control also is variable, some patients requiring one or two doses per day, others three or four.

Patients show marked differences in the incidence and severity of side-effects. There also is a difference in the ability of various patients to tolerate side-effects. Minor discomforts which will be treated as of no consequence by a stoical patient may assume disabling proportions in a more . . . [Full Text PDF of this Article]

Author Affiliations
Washington, D. C.

From the Veterans Administration Hospital and the Cardiovascular Research Laboratory, Department of Medicine, Georgetown University School of Medicine.

Footnotes
Received for publication June 25, 1956.

Read before the Section on Experimental Medicine and Therapeutics Symposium on the Management of Hypertension at the 105th Annual Meeting of the American Medical Association, Chicago, June 12, 1956.

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