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IX. Carbohydrate Metabolism in the Chronic Alcoholic Psychoses

MARK D. ALTSCHULE, M.D.; MAURICE VICTOR, M.D.; PHYLLIS D. HOLLIDAY

AMA Arch Intern Med. 1957;99(1):40-46.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Earlier work has shown that patients with schizophrenic, manic-depressive, and involutional psychoses have a disorder of carbohydrate metabolism ¹ that is indistinguishable from one exhibited by nonpsychotic patients with a chronic brain disease, i. e., multiple sclerosis.² The present report describes certain aspects of carbohydrate metabolism in another brain disease—chronic alcoholic psychosis. Actually, the patients discussed here constituted two groups: (a) those with Korsakoff's psychosis and (b) those with chronic auditory hallucinosis associated with alcoholism.

Material and Methods

Nine patients were studied; all were women. One group consisted of four patients, aged 31, 49, 60, and 62 years, respectively, with the classic features of Korsakoff's psychosis—impairment of memory, confabulation, and an inability to learn and retain newly presented material. All four patients had a background of serious alcoholism and still showed the stigmata of a previous attack of Wernicke's encephalopathy in the form of horizontal nystagmus and slight ataxia. . . . [Full Text PDF of this Article]

Author Affiliations
Waverley, Mass.; Boston; Waverley, Mass.

From the Laboratory of Clinical Physiology, McLean Hospital, Waverley, Mass., the Department of Neurology, Massachusetts General Hospital, Boston, and the Departments of Medicine and Neurology, Harvard Medical School, Boston.

Footnotes
Submitted for publication May 24, 1956.

This study was aided in part by a Research Grant (M767) from the National Institutes of Health (Neurological Diseases and Blindness), Public Health Service.

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