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Successful Treatment with Cortisone

ANDRÉ de VRIES, M.D.; BERNARD BORNSTEIN, M.D.; ELIEZER FRIEDMAN, M.D.

AMA Arch Intern Med. 1957;99(6):1001-1005.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the pioneer work of Head and Holmes,¹ the physiological and psychological aspects of central pain have been the subject of many studies. Central pain is of specific character: It is severe, it is of burning quality, it affects the whole personality and may cause changes in behavior, it is aggravated by emotional influences and sensory stimuli, and it is generally not alleviated by the usual analgetics. Frequently the pain does not leave the patient during the night and may be so severe as to lead to suicide. At times it is accompanied by vasomotor and trophic disturbances.

In spite of numerous clinical and experimental investigations, complete understanding of the problem of central pain has not yet been achieved. Since the work of Dejerine and Roussy,² the thalamus and its cerebral connections are held responsible for the central pain sensation.

The mechanism by which damage to the thalamus . . . [Full Text PDF of this Article]

Author Affiliations
Petah Tikva, Israel

From the Department of Medicine D, the Department of Neurology, and the Department of Roentgenology, Beilinson Hospital of the Labour Sick Fund.

Footnotes
Submitted for publication July 22, 1956.

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