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EDWIN A. LOCKE, M.D.

Arch Intern Med. 1915;XV(5 1):659-713.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since the original papers of Bamberger¹²,¹³ (1889 and 1891) and Marie¹¹³ (1890) numerous reports have been published which have more and more definitely established this morbid condition as a distinct clinical entity among the general group of allied diseases, including leontiasis ossae, osteitis deformans, acromegaly, rickets, syphilis of the bones and others. Walters²¹⁰ (1896), Massalongo¹¹⁷ (1897), Janeway⁸⁸ (1903), Thompson¹⁹² (1904), Wynn²¹⁸ (1904), Ebstein⁴⁸ (1906) and Alexander³ (1906) have each collected the typical cases from the literature and given a critical review, together with a general discussion of the diseases. In spite of these and many other excellent reports, much regarding the cause, course and real nature of the pathologic changes remains obscure.

The object of the present report is to record the results of the study of five typical cases for a period of years with reference to such con . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

Footnotes
Submitted for publication Oct. 3, 1914.

The Roentgen-ray studies were largely made in the Roentgen-ray Department of the Boston City Hospital under the direction of Dr. Francis H. Williams, to whom I am deeply indebted for constant cooperation and advice. My thanks are also due Dr. Walter Dodd of the Massachusetts General Hospital, and Dr. George H. Holmes of the Long Island Hospital, for the examinations made of the cases from those institutions.

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